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General Anesthesia and the Neural Correlates of Consciousness

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Applied AnesthesiaNCCTheory testing

By Michael T. Alkire, Andrew G. Hudetz, and Giulio Tononi

Summary

Reviews how anaesthetics disrupt corticocortical and thalamocortical integration. Links anaesthetic mechanisms to IIT (integration disruption) and GNW (frontoparietal decoupling). Anesthesia = powerful experimental tool for controlling consciousness states.

Why It Matters

The definitive review establishing "anesthetic neurology" — using controlled LOC to test competing theories of consciousness.

Notes

This entry is a seed import from the Phase 1 Knowledge Inventory. It has not yet been manually reviewed.