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By Marcus E. Raichle, Ann M. MacLeod, Abraham Z. Snyder, William J. Powers, Debra A. Gusnard, and Gordon L. Shulman

Summary

Identified a set of brain regions (mPFC, PCC/precuneus, angular gyri, MTL) consistently more active during passive rest than during task performance. This "default mode" correlates with self-reflection, autobiographical memory, and mind-wandering.

Why It Matters

Transformed neuroscience by showing the brain is intrinsically active, not merely stimulus-responsive. DMN is central to self-consciousness, psychedelic action, and meditation.

Notes

This entry is a seed import from the Phase 1 Knowledge Inventory. It has not yet been manually reviewed.